2023 · npj Flexible Electronics
2019
Review Trends in Biotechnology
Wearable Devices for Single-Cell Sensing and Transfection
L. Chang† , Y. Wang† , F. Ershad† , R. Yang , C. Yu , Y. Fan
† These authors contributed equally.
Abstract
Wearable healthcare devices are mainly used for biosensing and transdermal delivery. Recent advances in wearable biosensors allow for long-term and real-time monitoring of physiological conditions at a cellular resolution. Transdermal drug delivery systems have been further scaled down, enabling wide selections of cargo, from natural molecules (e.g., insulin and glucose) to bioengineered molecules (e.g., nanoparticles). Some emerging nanopatches show promise for precise single-cell gene transfection in vivo and have advantages over conventional tools in terms of delivery efficiency, safety, and controllability of delivered dose. In this review, we discuss recent technical advances in wearable micro/nano devices with unique capabilities or potential for single-cell biosensing and transfection in the skin or other organs, and suggest future directions for these fields.
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L. Chang, Y. Wang, F. Ershad, R. Yang, C. Yu, Y. Fan (2019). Wearable Devices for Single-Cell Sensing and Transfection. Trends in Biotechnology 37(11), 1175–1188. https://doi.org/10.1016/j.tibtech.2019.04.001
BibTeX · Chang2019WearableDevices
@article{Chang2019WearableDevices,
title = {{Wearable Devices for Single-Cell Sensing and Transfection}},
author = {L. Chang and Y. Wang and F. Ershad and R. Yang and C. Yu and Y. Fan},
journal = {Trends in Biotechnology},
year = {2019},
volume = {37},
number = {11},
pages = {1175--1188},
doi = {10.1016/j.tibtech.2019.04.001},
url = {https://doi.org/10.1016/j.tibtech.2019.04.001},
}